ISAT ANEURYSM PDF

Memi The primary outcome was death or dependence at 1 year defined by a modified Rankin scale of Long-term angiographic recurrences after selective endovascular treatment of aneurysms with detachable coils. Qureshi, Textbook of Interventional NeurologyEd. Lessons to be learnt from the international subarachnoid haemorrhage trial ISAT. J Neurol Neurosurg Psychiatry ; Secondary outcomes included rebleeding from the treated aneurysm and risk of seizures. Division of Neurosurgery, Sir Mortimer B. Could late rebleeding overturn the superiority of cranial aneurysm coil embolization over clip ligation seen in ISAT?

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International subarachnoid aneurysm trial ISAT of neurosurgical clipping versus endovascular coiling in patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.

Surg Neurol. We undertook a randomised, multicentre trial to compare these treatments in patients who were suitable for either treatment because the relative safety and efficacy of these approaches had not been established. Here we present clinical outcomes 1 year after treatment. The primary outcome was death or dependence at 1 year defined by a modified Rankin scale of Secondary outcomes included rebleeding from the treated aneurysm and risk of seizures. Long-term follow up continues. Analysis was in accordance with the randomised treatment.

FINDINGS: We report the 1-year outcomes for of patients allocated to endovascular treatment, and of patients allocated to neurosurgical treatment. The risk of epilepsy was substantially lower in patients allocated to endovascular treatment, but the risk of late rebleeding was higher. INTERPRETATION: In patients with ruptured intracranial aneurysms suitable for both treatments, endovascular coiling is more likely to result in independent survival at 1 year than neurosurgical clipping; the survival benefit continues for at least 7 years.

The risk of late rebleeding is low, but is more common after endovascular coiling than after neurosurgical clipping.

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ISAT: The International Subarachnoid Aneurysm Trail

We report the 1-year outcomes for of patients allocated to endovascular treatment, and of patients allocated to neurosurgical treatment. Intracranial aneurysm surgery and its future. Assessment of scales of disability and handicap for stroke patients. Long-term follow up continues. Isatt types of treatment are being used for patients with ruptured intracranial aneurysms: From Wikipedia, the free encyclopedia.

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ISAT ANEURYSM PDF

International subarachnoid aneurysm trial ISAT of neurosurgical clipping versus endovascular coiling in patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Surg Neurol. We undertook a randomised, multicentre trial to compare these treatments in patients who were suitable for either treatment because the relative safety and efficacy of these approaches had not been established. Here we present clinical outcomes 1 year after treatment. The primary outcome was death or dependence at 1 year defined by a modified Rankin scale of Secondary outcomes included rebleeding from the treated aneurysm and risk of seizures. Long-term follow up continues.

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International Subarachnoid Aneurysm Trial

Mayer S, Kreiter K. International subarachnoid aneurysm trial ISAT of neurosurgical clipping versus endovascular coiling in patients with ruptured intracranial aneurysms: We report the 1-year outcomes for of patients allocated to endovascular aneurgsm, and of patients allocated to neurosurgical treatment. Lessons to be learnt from the international subarachnoid haemorrhage trial ISAT. Role of angiography following aneurysm surgery. More on ISAT [letter]. From Wikipedia, the free encyclopedia.

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